Thursday, March 7, 2013

Coach Dies in Freak Accident, California High School in Mourning

Marion Adams - a multimedia teacher and track and field coach at Rio Londa High School in California - died this week in a terrifying bicycle accident, reports The Sacramento Bee.

The 59-year old was riding away from practice on Monday when he looked over his shoulder to bid farewell to a student.

Tragically, Adams therefore failed to see a partially opened metal gate in the school parking lot and could not slow down in time to avoid it.

He was impaled on the structure, rushed to Mercy San Juan Hospital and initially survived two surgeries to treat internal injuries before passing away.

"Marion was the most popular and nicest man on campus; just a great guy," Athletic Director Mike Morris told the newspaper. "It's a huge loss, devastating to our community.?

Hundreds attended a vigil held for Adams on Tuesday night.

Adams, who coached at his alma mater, is survived by wife Kathy, son Joe and daughter Sarah and two grandchildren.

Source: http://www.thehollywoodgossip.com/2013/03/coach-dies-in-freak-accident-california-high-school-in-mourning/

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Wednesday, March 6, 2013

Libyan army restores order at gas complex, flows suspended

MILAN/TRIPOLI (Reuters) - Libya said on Monday the army had restored order at an energy complex near Tripoli after weekend clashes between militia guards, but that gas exports to Italy would remain suspended and oil production cut back for several days.

Libyan officials said the national army and militias aligned with it had arrived at the Mellitah oil and gas complex, some 100 km (60 miles) west of Tripoli, on Sunday night. The locally deployed militias had ceased fighting but gas exports had been suspended on Monday for a third day.

"We have full control, it is safe, it is just a matter of assessing the situation to identify the one entity that will take charge of the security," said Abdulfattah Shagan, chairman of the Mellitah oil and gas venture between Libya's National Oil Corporation and Italy's Eni.

"I think the army will be in charge," he said adding that the fighting has done only minor damage to facilities.

Armed clashes erupted on Saturday after an argument between former rebel fighters from nearby Zuwara and others from Zintan over who should guard Mellitah, security officials said. Deputy Oil Minister Omar Shakmak said one person was killed and several injured.

The disruption at the Mellitah complex is the latest to hit the energy sector in Libya, where protests have shut down oil-export terminals in recent months, and comes after January's hostage-taking at an Algerian gas plant.

Thousands of former rebels who fought to overthrow former leader Muammar Gaddafi in 2011 have been employed in a protection force to look after Libyan oil and gas installations. Rivalries between militia and clan groups have posed a broader problem for Tripoli as it struggles to assert central control.

In recent months, activists and local militia have disrupted operations in Libya's main industry, pursuing goals such as better living conditions or more regional autonomy.

This has hurt OPEC member Libya's oil output, which had returned to pre-war levels of 1.6 million barrels per day (bpd) relatively fast after the 2011 revolution, but has been hit by disruptions since then.

RESTART DUE IN DAYS

Mellitah supplies Italy with gas through the Greenstream pipeline, which ends at the Sicilian port town of Gela and at full capacity pumps at least 8 billion cubic meters a year.

Shagan told Reuters that in addition to a full suspension of gas production at the Mellitah complex, the venture had to reduce oil output at its Elephant and Wafa fields by 25 percent.

That could rise to 50 percent from regular output of 210,000 barrels per day, he added.

"Once we establish full security, then we will start bringing back our staff and preparing to start up. It will take three to four days altogether," he added.

A spokesman for ENI said the plant had restarted on Monday to process small gas flows. A source close to the matter said it would take several days to ramp up processing.

Italy gets most of its gas from Algeria, Russia, and Libya - which provides between 10 and 15 percent - while some comes from Norway and the Netherlands.

Italy will compensate for the Libyan gas stoppage by raising imports from the Russian and Dutch pipelines, analysts said.

The halt in Libyan supply coincided with large scale gas supply falls due to unexpected pipeline outages in the North Sea, which at one point on Monday propelled British spot gas prices to five-year highs.

Unlike Britain, where most of the gas sold is on the spot market, Italy gets most of its gas through long-term contracts linked to the oil price.

Italy saw its gas imports from Libya suspended for several months during the 2011 civil war that ultimately led to the fall of former leader Muammar Gaddafi.

(Reporting by Marie-Louise Gumuchian, Ali Shuaib, Stephen Jewkes and Giancarlo Navach; Editing by Anthony Barker and Robin Pomeroy)

Source: http://news.yahoo.com/libyan-army-restores-order-gas-complex-flows-suspended-182611693--finance.html

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Tuesday, March 5, 2013

Misplaced molecules: New insights into the causes of dementia

Monday, March 4, 2013

A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).

ALS is an incurable neurological disease which manifests as rapidly progressing muscle wasting. Both limbs and respiratory muscles are affected. This leads to impaired mobility and breathing problems. Patients commonly die within a few years after the symptoms emerged. In rare cases, of which the British physicist Stephen Hawking is the most notable, patients can live with the disease for a long time. In Germany estimates show over 150,000 patients suffering from ALS ? an average of 1 in 500 people.

Proteins gone astray

Over the last few years, there has been increasing evidence that ALS and FTD ? a form of dementia associated with changes in personality and social behaviour ? may have similar or even the same origins. The symptoms overlap and common factors have also been found at the microscopic level. In many cases, particles accumulate and form clumps in the patient's nerve cells: this applies particularly to the TDP-43 protein.

"Normally, this protein is located in the cell nucleus and is involved in processing genetic information," explains molecular biologist Dr. Bettina Schmid, who works at the DZNE Munich site and at LMU. "However, in cases of disease, TDP-43 accumulates outside the nucleus forming aggregates." Schmid explains that it is not yet clear whether these clumps are harmful. "However, the protein's normal function is clearly disrupted. It no longer reaches the nucleus to perform its actual task. There seems to be a relationship between this malfunction and the disease."

Studies on zebrafish

However, until now little was known about the function of TDP-43. What are the consequences when this protein becomes non-functional? In order to answer this question, the team led by Bettina Schmid cooperated with the research group of Prof. Christian Haass to investigate the larvae of specially bred zebrafish. Their genetic code had been modified in such a way that no TDP-43 was produced in the organism of the fish. The result: the young fish showed massive muscle wasting and died a few days after hatching. Moreover, the extensions of the nerve cells which control the muscles were abnormal.

"To some extent, these are symptoms typical of ALS and FTD. Therefore, a loss of function of TDP-43 does seem to play a critical role in the disease," says Haass, Site Speaker of the DZNE Munich Site and chair of Metabolic Biochemistry at LMU.

The study revealed one more finding which surprised the researchers: the blood flow of the fish was massively disturbed. "It is well known that circulatory disorders play a part in other forms of dementia, notably in the case of Alzheimer's," says Haass. "We now want to investigate whether such problems with blood flow may be a general problem of neurodegenerative diseases and whether such problems occur particularly in patients with ALS and FTD."

###

Helmholtz Association of German Research Centres: http://www.helmholtz.de/en/index.html

Thanks to Helmholtz Association of German Research Centres for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127105/Misplaced_molecules__New_insights_into_the_causes_of_dementia

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Thursday, February 21, 2013

Ofcom announces 4G spectrum winners in the UK, snags less cash than expected

Ofcom announces 4G spectrum winners in the UK, snags less cash than expected

UK regulator Ofcom has revealed the winners of its 4G spectrum auction after more than 50 rounds of bidding: EE, Hutchison 3G (Three), BT subsidiary Niche Spectrum Ventures, Telefonica (O2) and Vodafone. It wasn't all good news however, as the agency revealed the auction only roped in £2.4 billion pounds, less than the £3.5 billion it had anticipated. Left on the outside looking in? MLL Telecom and HKT Company. Interestingly enough it was Vodafone -- headed by CEO Vittorio Colao who famously suggested only "technofreaks" were into 4G speed -- that spent the most.

The idea is to spread high speed wireless across "almost the whole" UK population by 2017 at the latest, and the auction's intent was to create more competition in the space. Telefonica UK specifically is required to provide indoor reception to at least 98 percent of the population by then, as a condition of its bid. As seen above, the available 250MHz of spectrum was auctioned off in two separate bands, 800MHz (ideal for expanded coverage and freed up by the digital TV transition) and 2.6GHz more suited to high speed data connections. So what's next? You guessed it -- another round of bidding, to determine where in each band the winners spectrum lies, before services roll out in spring or summer of this year. Hit the source link to check out the full results for yourself and prepare for the 5G battle, expected to commence sometime after 2018.

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Source: Ofcom

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/IKidLBd9cFc/

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Wednesday, February 20, 2013

Sony reveals PlayStation 4, fires first shot in the next console war

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After months of rumor and speculation, Sony has revealed its new game machine ? the PlayStation 4 ? as well as a new controller with a touchpad, a "share" button and light bar.

"Today marks a moment of truth and a bold step forward for PlayStation as a company," said Andrew House, president and Group CEO of Sony Computer Entertainment, as he took the stage at the Hammerstein Ballroom in New York City on Wednesday. "Today we will give you a glimpse into the future of play."

House told a room packed full of journalists that the new machine ? the successor to the PlayStation 3 ? would take the moniker PlayStation 4. Sony then revealed the new touch-sensing DualShock controller as well as a new "stereo camera" that works in conjunction with the controller (see video below.)

Sony said the PlayStation 4 will launch "holiday 2013" but did not reveal a specific date or a price. Sony also did not show off what its new gaming hardware will look like, revealing only the controller and pictures of the new camera.

Mark Cerny, the PS4's lead system architect, did outline some of the innards that will be powering the machine explaining, ?The architecture we chose is like a PC in many ways.?

He said the PlayStation 4 will feature an X86 CPU and a whopping 8 gigabytes of unified system memory. (For more on that, check out our story here.)

David Perry ? CEO and founder of Gaikai ? also took the stage Wednesday. Sony bought his game streaming company last year. He explained that integration of the streaming service with the PlayStation Store will allow gamers to instantly try games before they buy them.

Meanwhile, Perry said that with the "share" button on the new PS4 controller players will be able to live broadcast their gameplay to their PlayStation Network friends.

He said friends will not only be able to watch your game in action, but can post comments to your screen as you play (if you let them). You'll also be able to allow friends to take over your game so they can, say, assist you in a difficult area or interact with your game in other helpful ways.

"What we?re creating is the fastest, most powerful network for gaming in the world," Perry said. "Our vision is to create the first social gaming network with meaning."

Perry also revealed Remote Play ? a feature that will allow gamers to take their PS4 action to Sony's smaller game screen. That is, if you're in the middle of playing a game on your PS4, you can use Remote Play to instantly transfer your game to Sony's handheld PS Vita.

Perry said the ultimate goal is to make it so all PS4 games will be playable on the Vita.

So what games will be coming to the PlayStation 4? Bungie ? the creator of the Xbox-exclusive Halo game franchise ? revealed it will be bringing its newly revealed project "Destiny" to the PlayStation 4 (with an edition also for the PlayStation 3).

Hermen Hulst, co-founder of Guerrilla Games, introduced "Killzone: Shadowfall" a stunning looking futuristic shooter. And Matt Southern from Evolution Studios showed off the ultra-realistic "Drive Club" racing game.

"We?ve gone borderline insane with the real-world details," Southern said, pointing out the ultra-fine detail that can be seen on the cars in the game.

Meanwhile, Sucker Punch's Nate Fox revealed the new game from the studio that brought us the "InFamous" series. He said "InFamous" Second Son" ? a game about what happens when super powers and the power of surveillance collide ? will be a PlayStation 4 exclusive.

Respected indie developer Jonathan Blow ? the creator of the critically acclaimed game "Braid" ? showed off his next game "The Witness." He said the puzzle-filled title will be a PlayStation 4 "launch window" game.

Ubisoft's Yves Guillemot revealed what everyone expected ? that the developer's highly anticipated game of surveillance and hacking called "Watch Dogs" is planned for the next-gen PlayStation 4.

In something of a surprise, PC gaming stalwart Blizzard revealed that it'll be bringing "Diablo 3" to both the PlayStation 4 and the PlayStation 3.

And it appears that Sony won?t be saying goodbye to its oft-ignored PlayStation Move motion controller. Media Molecule ? the developers behind the ?LittleBigPlanet? games ? showed off a tool that enables players to use the Move controller and the PS4 to craft digital sculptures and bring them to life.

Sony, Microsoft and Nintendo have been duking it out for years, vying to be the prime purveyor of home video games and, in recent years, other home entertainment as well. But Sony's news today is the opening shot in an all new console war.

It's been six years since Sony launched the PlayStation 3 and seven years since Microsoft launched its competing Xbox 360. Late last year, Nintendo revealed the Wii U ? its new home game machine and the successor to the Wii. But so far, the Wii U's lackluster sales and technical specs that make it seem more on par with the current generation Xbox 360 and PlayStation 3, suggest this machine is more of an interim step in the three-way gaming battle.

With Microsoft rumored to be working on its own new home game console (which it will reportedly unveil in the coming weeks), it is Sony and Microsoft that are widely expected to go head-to-head in the coming years, vying for the same demographic and to become the all-important entertainment hub in your household.

Winda Benedetti writes about video games for NBC News. You can follow her tweets about games and other things on Twitter here @WindaBenedetti and you can follow her on Google+. Meanwhile, be sure to check out the IN-GAME FACEBOOK PAGE to discuss the day's gaming news and reviews.

Source: http://www.nbcnews.com/technology/ingame/sony-reveals-playstation-4-fires-first-shot-next-console-war-1C8452386

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MOS Magnetic Cable Organizer Magnetizes Your Cords and Holds Them Anywhere

MOS Magnetic Cable Organizer Magnetizes Your Cords and Holds Them AnywhereA number of cables stick to magnets automatically, but some need a little help to stay put. The MOS Magnetic Cable organizer adds magnet clips to your cables for easier identification and so they quickly attach to a metal base plate for quick access.

The MOS organizer doesn't take much effort to set up: you just clip little magnet tags onto the cables that need them (e.g. an micro-USB cable and not a MagSafe cable), then lay the tagged cable on the metal base. It'll stick around, nicely organized, until you decide to just gently remove it for use.

Want a DIY version? While it won't add extra magnetic pull to your cables like the MOS' clips, this magnetic binder clip hack costs very little to implement and serves a similar purpose. It's definitely worth a look if you don't want to spend the money.

MOS Magnetic Cable Organizer ($20) | Amazon via Apartment Therapy Tech

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/XWuc_54jsrM/mos-magnetic-cable-organizer-magnetizes-your-cords-and-holds-them-anywhere

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The Filibuster Solution, Or 'What If Honeybees Ran The U.S. Senate?'

Bees are democrats. They vote. When a community of bees has to make a choice, like where to build a new hive, they meet, debate and decide. But here's what they don't do: they don't filibuster. No single bee (or small band of bees) will stand against the majority, insisting and insisting for hours. They can't.

Bee biology prevents it.

U.S. Senators, listen up here. According to Professor Tom Seeley, an entomologist at Cornell University, a hive will send a few hundred "scouts" into a back yard, or into the woods, to find a good nest site. If a particular scout thinks that an elm tree ? that one over there ? is the best place to build a hive, she will say so, by dancing. Her dance will tell the other bees where to find that special tree ...

If she feels really strongly, she will dance with extra energy, for a longer time.

Even if most of the other bees have chosen a different tree, they won't stop her dance, or tell her to be quiet. Or have three-fifths of them invoke "cloture," a fancy way of saying "shut up." They will wait her out.

Then something astonishing happens. I've written about it before, but I want to mention it again, now that our Senators are mulling their next filibuster, because what bees do makes democracy much, much easier ? or so it seems.

Different scouts will dance for their different trees. Gradually, a favorite emerges. But what if a particular bee is totally convinced that the tree she has found is so superior that she just keeps dancing and dancing, and won't stop? How does the hive handle a stubborn bee?

The Jimmy Stewart Bee

"We haven't seen any bees like that," Professor Seeley said. None? None, he told me. "In the world of scout bees, you don't have die-hard bees that just dance and dance and dance forever." Why not?

Because, he said, even if a bee feels very, very strongly about her choice and has danced feverishly for as long as she could, once she's done ? and no bee can dance forever ? she apparently stops caring.

Her enthusiasm drains out of her ? Imagine Jimmy Stewart, the young Senator in Mr. Smith Goes To Washington making one glorious big speech, and then plopping down in his chair, dull and blank as a piece of chalk.

The 'Retire And Rest' Hypothesis

That, says Professor Seeley, is what happens to scout bees. They've "voted," they've danced. The other bees are free to visit her tree and see for themselves. But now that she's done her part, her sense of urgency dribbles away. She stops campaigning ...

... and no longer champions her cause. When the decision is made, she will go with the majority choice, whatever it turns out to be. It's not like she's giving up. She's probably wired this way.

As Professor Seeley puts it, there may be "an internal, neurophysiological process that causes every scout to gradually and automatically lose her motivation to dance for a site, even one that is high in quality."

And this is built in?

"[It's] built in," says Seeley. He calls this his Retire and Rest hypothesis. "And when you think about it," he says, "that works really well."

Well, if "working well" means getting rid of fractious, irritating bees who frustrate the majority, hobble government, paralyze the system, then yup, the absence of passion works wonderfully.

But what if that irritating bee is right? What if her tree is the better site?

That can happen, but generally, says Professor Seeley, bee hives choose well. In his book Honeybee Democracy, he says given the array of choices, most hives avoid disastrous sites and choose pretty good ones. So the system works ? for bees.

So would we be better off being more beelike?

Each of us would be free to choose, free to express his choice, free to gather, but once we voted, we'd lose our passion. No resenting the winners. No scheming. No grumbling. No sabotage. No filibusters. We'd go with the flow.

To some degree, we do that already. Democrats suffered through eight long years of Bush. Republicans are now plodding through eight long years of Obama. The difference is, if we were bees, we wouldn't suffer. We'd just cooperate. Automatically.

Biologically-induced congeniality sounds like a nice alternative to what we've got now, a spitting, snarling mosh pit of politicians. But even so, I don't wish a bee lobotomy on our senators.

Yes, they are petty, shortsighted blowhards too much of the time. Some have lost the art of compromise. But would I prefer the bee model? A polite, genetically induced quiet? No, I wouldn't.

I see the advantages, but speaking as an intelligent, free willed mammal, I'm afraid their system seems a little ... umm, what's the word?

Inhuman.

In 2011, I spoke with Professor Seeley on Morning Edition, and if you want to hear that interview and listen to bees debating (the "bees" courtesy of jazz violinist Mazz Swift-Camlet) just click here, then on the "listen" button. The bee drawings ? which I'm reprising from the 2011 post ? come from NPR's very own reporter, composer, illustrator and honorary bee, Adam Cole.

Source: http://www.npr.org/blogs/krulwich/2013/02/19/172385254/the-filibuster-solution-or-what-if-honeybees-ran-the-u-s-senate?ft=1&f=1007

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